Research

W3.CSS

Research

Research conducted by the Pet Nutrition team at the Ontario Veterinary College focuses on how advances in nutrition can optimize the life of pets, utilizing the voluntary recruitment of client-owned hospital patients, on-campus research facilities and our specialized team.

Special areas of interest include canine and feline metabolism, microbiome and metabolomics, obesity and body composition, nutrient bioavailability in disease process, client communication and special interests, as well as growing ingredient and feeding trends. Some of the research technology utilized by our highly-skilled team includes Duel-energy X-Ray absorptiometry (DEXA) and indirect calorimetry.

The effects of camelina oil on skin and coat quality and overall health in adult dogs

TRrecruitment The Shoveller laboratory in the department of Animal Biosciences will be conducting a study to investigate the effects of Camelina oil, canola oil or flax oil on skin and coat quality and overall health in adult dogs. They are currently recruiting healthy, adult dogs between the ages of 3-15 years old.

Dogs enrolled in this study will be provided with kibble for 5 months, in addition to complementary bloodwork and baths. For more information, please click on the included poster, or email Taylor Richards (tricha16@uoguelph.ca) .

Examining the nutritional adequacy of plant-based diets

recruitment poster We want to feed your dogs! We are currently recruiting healthy, neutered adult dogs to assist in the study of the nutritional adequacy of meat-based and plant-based diets. This study will compare a plant-based and a conventional meat-based kibble through laboratory sampling.

Dogs enrolled in this study will be provided with kibble for over 4 months, in addition to complementary physical exams, bloodwork and imaging. For more information, please visit: https://bulletin.ovc.uoguelph.ca/post/185343119565/we-want-to-feed-your-dogs-study-will-compare

We are currently recruiting healthy adult dogs for two research trials. Please go to “Research – Recruitment Ongoing” to read more about these exciting opportunities!

Chen, T., Khosa, D., Abood, S. K., McEwen, S., & McWhirter, J. (2020). Readability and Content of Online Pet Obesity Information. Journal of the American Veterinary Medical Association. In Press.

DiSabatino, B., Parr, J. M., Kritikos, G., Monteith, G., & Verbrugghe, A. (2020). Storage temparature does not affect thiamine concentrations in twelve extruded feline diets during one-year storage. Canadian Veterinary Journal. In Press.

Kamleh, M. (2020). A cross-sectional study of diet motives and attitudes towards nutrition guidance received from veterinarians. The Veterinary Record. In Press.

Sutherland, K., Cargo-Froom, C., Verbrugghe, A., & Shoveller, A. K. (2020). Equations used to develop commercial dog food feeding guidelines and Canadian owner feeding practices in 2018. Canadian Veterinary Journal. In Press.

Grant, C. E., Shoveller, A. K., Blois, S., Bakovic, M., Monteith, G., & Verbrugghe, A. (2020). Dietary intake of amino acids and vitamins compared to NRC requirements in obese cats undergoing energy restriction for weight loss. BMC Veterinary Research, 16, 426. https://doi.org/10.1186/s12917-020-02649-0

Camara, A., Verbrugghe, A., Cargo-Froom, C., Hogan, K., DeVries, T. J., Sanchez, A., Robinson, L. E., & Shoveller, A. K. (2020). The daytime feeding frequency affects appetite-regulating hormones, amino acids, physical activity, and respiratory quotient, but not energy expenditure, in adult cats fed regimens for 21 days. PloS One, 15(9). https://doi.org/10.1371/journal.pone.0238522

Rankovic, A., Adolphe, J. L., Ramdath, D. D., Shoveller, A. K., & Verbrugghe, A. (2020). Glycemic response in non-racing sled dogs fed single starch ingredients and commercial extruded dog foods with different carbohydrate sources. Journal of Animal Science, 98(8), 1-11. https://doi.org/10.1093/jas/skaa241

Lyu, Y., Su, C., Verbrugghe, A., Van de Wiele, T., Martos Martinez-Caja, A., & Hesta, M. (2020). Past, present, and future of gastrointestinal microbiota research in cats. Frontiers in Microbiology, 11, 1161. https://doi.org/10.3389/fmicb.2020.01661

Dodd, S. A., Cave, N. J., Abood, S. K., Shoveller, A. K., Adolphe, J. L., & Verbrugghe, A. (2020). An observational study of pet feeding practices and how these have changed from 2008 to 2018. Veterinary Record. http://dx.doi.org/10.1136/vr.105828

Kamleh, M. K., Khosa, D. K., Dewey, C. E., Verbrugghe, A., & Stone, E. A. (2020). Ontario Veterinary College first-year students’ perceptions of companion animal nutrition and their own nutrition: Implications for a veterinary nutrition curriculum. Journal of Veterinary Medical Education. Advance online publication. https://doi.org/10.3138/jvme.0918-113r1

Santarossa, A., Gibson, T. W., Kerr, C., Monteith, G. J., Durzi, T., Gowland, S., & Verbrugghe, A. (2020). Body composition of medium to giant breed dogs with or without cranial cruciate ligament disease. Veterinary Surgery, 49(4). Advance online publication. https://doi.org/10.1111/vsu.13434

Bianco, A. V., Abood, S., Mutsaers, A., Woods, J. P., Coe, J. B., & Verbrugghe, A. (2020). Unconventional diets and nutritional supplements are more common in dogs with cancer compared to healthy dogs: An online global survey of 345 dog owners. Veterinary and Comparative Oncology. Advance online publication. https://doi.org/10.1111/vco.12599

Tal, M., Weese, J. S., Gomez, D. E., Hesta, M., Steiner, J. M., & Verbrugghe, A. (2020). Bacterial fecal microbiota is only minimally affected by a standardized weight loss plan in obese cats. BMC Veterinary Research, 16, 112. https://doi.org/10.1186/s12917-020-02318-2

Coe, J. B., O’Connor, R. E., MacMartin, C., Verbrugghe, A., & Janke, K. A. (2020). Effects of three diet history questions on the amount of information gained from a sample of pet owners in Ontario, Canada. Journal of the American Veterinary Medical Association, 256(4), 469-478. https://doi.org/10.2460/javma.256.4.469

Kamleh, M. K., Khosa, D. K., Dewey, C. E., Verbrugghe, A., & Stone, E. A. (2020). The perceived importance, emphasis, and confidence in veterinary nutrition education of first-year Canadian and US veterinary students. Medical Science Educator, 30, 323-330. https://doi.org/10.1007/s40670-019-00908-w

Rankovic, A., Adolphe, J. L., & Verbrugghe, A. (2019). Letters to the Editor: The Authors Respond: Questions benefits of high carbohydrate content in canine diets. Journal of the American Veterinary Medical Association, 255(10), 1110-1112. https://doi.org/10.2460/javma.255.10.1110

Coe, J. B., Rankovic, A., Edwards, T. R., & Parr, J. M. (2019). Dog owner’s accuracy measuring different volumes of dry dog food using three different measuring devices. The Veterinary Record, 185(19), 599. http://dx.doi.org/10.1136/vr.105319

Rankovic, A., Adolphe, J. L., & Verbrugghe, A. (2019). Role of carbohydrates in the health of dogs. Journal of the American Veterinary Medical Association, 255(5), 546-554. https://doi.org/10.2460/javma.255.5.546

Kelly, D. M., Adolphe, J. L., Vernouillet, A., McCausland, J. A., Rankovic, A., & Verbrugghe, A. (2019). Motoric self-regulation by sled dogs and pet dogs and the acute effect of carbohydrate source in sled dogs. Animal Cognition, 22(6), 931-946. https://doi.org/10.1007/s10071-019-01285-y

Dodd, S., Barry, M., Grant, C., & Verbrugghe, A. (2019). Abnormal bone mineralization in a puppy fed an imbalanced raw meat homemade diet diagnosed and monitored using dual‐energy X‐ray absorptiometry. Journal of Animal Physiology and Animal Nutrition. https://doi.org/10.1111/jpn.13118

Tiffany, S., Parr, J. M., Templeman, J., Shoveller, A. K., Manjos, R., Yu, A., & Verbrugghe, A. (2019). Assessment of dog owners’ knowledge relating to the diagnosis and treatment of canine food allergies. The Canadian Veterinary Journal, 60(3), 268-274. https://europepmc.org/article/PMC/6380261

Dodd, S. A., Cave, N. J., Adolphe, J. L., Shoveller, A. K., & Verbrugghe, A. (2019). Plant-based (vegan) diets for pets: A survey of pet owner attitudes and feeding practices. PloS One, 14(1). https://doi.org/10.1371/journal.pone.0210806

Mansilla, W. D., Marinangeli, C. P., Ekenstedt, K. J., Larsen, J. A., Aldrich, G., Columbus, D. A., Weber, L., Abood, S. K. & Shoveller, A. K. (2019). Special topic: The association between pulse ingredients and canine dilated cardiomyopathy: addressing the knowledge gaps before establishing causation. Journal of animal science, 97(3), 983-997. https://doi.org/10.1093/jas/sky488

Tal, M., Parr, J. M., MacKenzie, S., & Verbrugghe, A. (2018). Dietary imbalances in a large breed puppy, leading to compression fractures, vitamin D deficiency, and suspected nutritional secondary hyperparathyroidism. The Canadian Veterinary Journal, 59(1), 36-42. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731398/

Dodd, S. A., Adolphe, J. L., & Verbrugghe, A. (2018). Plant-based diets for dogs. Journal of the American Veterinary Medical Association, 253(11), 1425-1432. https://doi.org/10.2460/javma.253.11.1425

Santarossa, A., Parr, J. M., & Verbrugghe, A. (2018). Assessment of canine and feline body composition by veterinary health care teams in Ontario, Canada. The Canadian Veterinary Journal, 59(12), 1280-1286. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237266/

Kritikos, G., Weidner, N., Atkinson, J. L., Bayle, J., Van Hoek, I., & Verbrugghe, A. (2018). Quantification of vitamin D3 in commercial dog foods and comparison with Association of American Feed Control Officials recommendations and manufacturer-reported concentrations. Journal of the American Veterinary Medical Association, 252(12), 1521-1526. https://doi.org/10.2460/javma.252.12.1521

Reid, M. M., Verbrugghe, A., & Shoveller, A. K. (2018). Concentrations of calcium, phosphorus, and vitamin D in human foods are not different among 4 food databases. The Canadian Veterinary Journal, 59(2), 174-177. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764202/

Westgarth, S., Blois, S. L., Wood, R. D., Verbrugghe, A., & Ma, D. W. (2017). Effects of omega‐3 polyunsaturated fatty acids and aspirin, alone and combined, on canine platelet function. Journal of Small Animal Practice, 59(5), 272-280. https://doi.org/10.1111/jsap.12776

Xu, J., Verbrugghe, A., Lourenço, M., Cools, A., Liu, D. J., Van de Wiele, T., Marzorati, M., Eeckhaut, V., Van Immerseel, F., Vanhaecke, L., Campos, M., & Hesta, M. (2017). The response of canine faecal microbiota to increased dietary protein is influenced by body condition. BMC Veterinary Research, 13(1), 374. https://doi.org/10.1186/s12917-017-1276-0

Kritikos, G., Parr, J. M., & Verbrugghe, A. (2017). The role of thiamine and effects of deficiency in dogs and cats. Veterinary Sciences, 4(4), 59. https://doi.org/10.3390/vetsci4040059

Verbrugghe, A., & Hesta, M. (2017). Cats and carbohydrates: The carnivore fantasy? Veterinary Sciences, 4(4), 55. https://doi.org/10.3390/vetsci4040055

Weidner, N., & Verbrugghe, A. (2017). Current knowledge of vitamin D in dogs. Critical Reviews in Food Science and Nutrition, 57(18), 3850-3859. https://doi.org/10.1080/10408398.2016.1171202

Tal, M., Verbrugghe, A., Gomez, D. E., Chau, C., & Weese, J. S. (2017). The effect of storage at ambient temperature on the feline fecal microbiota. BMC Veterinary Research, 13(1), 256. https://doi.org/10.1186/s12917-017-1188-z

Weidner, N., Woods, J. P., Conlon, P., Meckling, K. A., Atkinson, J. L., Bayle, J., Makowski, A. J., Horst, R. L., & Verbrugghe, A. (2017). Influence of various factors on circulating 25(OH) vitamin D concentrations in dogs with cancer and healthy dogs. Journal of Veterinary Internal Medicine, 31(6), 1796-1803. https://doi.org/10.1111/jvim.14834

Santarossa, A., Parr, J. M., & Verbrugghe, A. (2017). The importance of assessing body composition of dogs and cats and methods available for use in clinical practice. Journal of the American Veterinary Medical Association, 251(5), 521-529. https://doi.org/10.2460/javma.251.5.521

Rajagopaul, S., Parr, J. M., Woods, J. P., Pearl, D. L., Coe, J. B., & Verbrugghe, A. (2016). Owners’ attitudes and practices regarding nutrition of dogs diagnosed with cancer presenting at a referral oncology service in Ontario, Canada. Journal of Small Animal Practice, 57(9), 484-490. https://doi.org/10.1111/jsap.12526

Xu, J., Verbrugghe, A., Lourenço, M., Janssens, G. P. J., Liu, D. J. X., Van de Wiele, T., Eeckhaut, V., Van Immerseel, F., Van de Maele, I., Niu, Y., Bosch, G., Junius, G., Wuyts, B., & Hesta, M. (2016). Does canine inflammatory bowel disease influence gut microbial profile and host metabolism? BMC Veterinary Research, 12, 114. https://doi.org/10.1186/s12917-016-0736-2

Schenkel, L. C., Sivanesan, S., Zhang, J., Wuyts, B., Taylor, A., Verbrugghe, A., & Bakovic, M. (2015). Choline supplementation restores substrate balance and alleviates complications of Pcyt2 deficiency. The Journal of Nutritional Biochemistry, 26(11), 1221-1234. https://doi.org/10.1016/j.jnutbio.2015.05.014

Verbrugghe, A., Janssens, G. P. J., Van de Velde, H., Cox, E., De Smet, S., Vlaeminck, B., & Hesta, M. (2014). Failure of a dietary model to affect markers of inflammation in domestic cats. BMC Veterinary Research, 10, 104. https://doi.org/10.1186/1746-6148-10-104

Van de Velde, H., Janssens, G. P. J., de Rooster, H., Polis, I., Peters, I., Ducatelle, R., Nguyen, P., Buyse, J., Rochus, K., Xu, J., Verbrugghe, A., & Hesta, M. (2013). The cat as a model for human obesity: insights into depot-specific inflammation associated with feline obesity. British Journal of Nutrition, 110(7), 1326-1335. https://doi.org/10.1017/S0007114513000226

Verbrugghe, A., & Bakovic, M. (2013). Peculiarities of one-carbon metabolism in the strict carnivorous cat and the role in feline hepatic lipidosis. Nutrients, 5(7), 2811-2835. https://doi.org/10.3390/nu5072811

Rochus, K., Janssens, G. P., Van de Velde, H., Verbrugghe, A., Wuyts, B., Vanhaecke, L., & Hesta, M. (2013). Highly viscous guar gum shifts dietary amino acids from metabolic use to fermentation substrate in domestic cats. British Journal of Nutrition, 109(6), 1022-1030. https://doi.org/10.1017/S0007114512003029

Hesta, M., Verbrugghe, A., Gulbrandsen, K. E., Christophe, A., Zentek, J., Hellweg, P., & Janssens, G. P. J. (2012). Biological effects of short-term salmon oil administration, using distinct salmon oil sources in healthy dogs. Journal of Small Animal Practice, 52(12), 699-704. https://doi.org/10.1111/j.1748-5827.2012.12000.x

Verbrugghe, A., Janssens, G. P. J., & Hesta, M. (2012). Palatability of different concentrations of a liquid nutritional supplement in healthy cats and dogs of different ages and breeds. Veterinarni Medicina, 57, 300-700. https://doi.org/10.17221/6017-VETMED

Depauw, S., Hesta, M., Whitehouse-Tedd, K., Vanhaecke, L., Verbrugghe, A., & Janssens, G. P. J. (2011). Animal fibre: The forgotten nutrient in strict carnivores? First insights in the cheetah. Journal of Animal Physiology and Animal Nutrition, 97(1), 146-154. https://doi.org/10.1111/j.1439-0396.2011.01252.x

Verbrugghe, A., Hesta, M., Daminet, S., & Janssens, G. P. J. (2011). Nutritional modulation of insulin resistance in the true carnivorous cat: a review. Critical Reviews in Food Science and Nutrition, 52(2), 172-182. https://doi.org/10.1080/10408398.2010.499763

Verbrugghe, A., Hesta, M., Daminet, S., Polis, I., Holst, J. J., Buyse, J., Wuyts, B., & Janssens, G. P. J. (2011). Propionate absorbed from the colon acts as gluconeogenic substrate in a strict carnivore, the domestic cat (Felis catus). Journal of Animal Physiology and Animal Nutrition, 96(6), 1054-1064. https://doi.org/10.1111/j.1439-0396.2011.01220.x

Verbrugghe, A., Paepe, D., Verhaert, L., Saunders, J., Fritz, J., Janssens, G. P. J., & Hesta, M. (2011). Metabolic bone disease and hyperparathyroidism in an adult dog fed an unbalanced homemade diet. Vlaams Diergeneeskundig Tijdschrift (Flemish Veterinary Journal), 80, 61-68. https://vdt.ugent.be/sites/default/files/art80108.pdf